Gene regulatory mechanisms in the launch process of T cell development
We’re honoured to welcome Dr. Ellen Rothenberg, Edward B. Lewis Professor of Biology at Caltech, for a special research seminar.
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Research Seminar: with Dr. Sid Goyal – Dimensionality in Living Systems
Meeting ID: 693 4383 4453
Passcode: 608808
Location:
Lecture Theatre B1009, Gordon B. Shrum Building (SHRM)
Modern biological experiments measure thousands of variables at once, making living systems appear overwhelmingly complex. Surprisingly, recent work shows that many biological processes can be described using only a few effective degrees of freedom. In this talk, I will use gene expression data from cell fate transitions in developing and regenerating tissues to explain what we mean by the effective dimensionality of a biological process and how it can be identified from data. Finally, I will make a case that this dimensionality may depend on the biological context and even the question of interest.
Dr. Sid Goyal’s Biography:
Sidhartha Goyal is a faculty in the Department of Physics, at the University of Toronto and CIFAR Fellow. His primary interest lies in developing mathematical and computational frameworks to quantify and uncover the rules that govern the structure of large populations of cells and subsequently their fate, from large microbial populations to stem cell differentiation and tissue regeneration to tumour progression. Sid got his PhD in Physics at Princeton and then moved to KITP, UC Santa Barbara for a postdoc. He got his first degree in Electrical Engineering from IIT Bombay.