Research Theme:
Cellular & Molecular Engineering, Imaging and Computational Biology,Research Interests:
gene regulation synthetic genomics; autoimmunity; heart disease machine learning; cancer; complex disease; genetics evolution; personalized medicine
Biography:
Dr. de Boer is an Assistant Professor in the School of Biomedical Engineering at the University of British Columbia. He did his PhD in the lab of Tim Hughes at the University of Toronto, and was a postdoctoral fellow in Aviv Regev’s lab at the Broad institute until the end of 2019, after which he moved to his current position at UBC. His research group aims to develop genomic and computational tools that will enable us to understand how the genome is regulated so that we can understand and treat disease.
RESEARCH EXCELLENCE
The Boer lab pioneers the integration of synthetic genomics and machine learning to unravel genome regulation complexities. Understanding genome regulation is now feasible with their innovative methods. They show that studying random DNA reveals how genomes function, as cells use the same mechanisms to interpret it similarly. The lab shows this potential by generating datasets exceeding genome size, providing deep insights into genome regulation.