SBME Research Day
SBME Research Day is an opportunity for our community of faculty, trainees, and staff to come together, discuss SBME priorities, and share their research through a poster session, trainee talks, and lunch. Save the date! More event details to come.
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Research Seminar: Beyond the Transcriptome: Proteome-Wide Overexpression Screening for Clinical Insight – Dr. Dae-Kyum Kim
Location:
Lecture Theatre B1001, Gordon B. Shrum Building – 6088 University Boulevard, Vancouver BC
This talk introduces BOGO, a novel proteome-wide gene overexpression platform designed to proactively identify cancer vulnerabilities that are often missed by traditional patient-data-driven methods. By systematically screening the entire human ORFeome in an isogenic cell line, this approach successfully uncovered clinically relevant genes that regulate cell proliferation and confer resistance to a wide range of chemotherapeutic drugs. The results validate this platform as a powerful tool for discovering novel therapeutic targets and developing rational combination therapies in personalized oncology and other complex diseases.